Uncommon Metastasis of a Glioblastoma Multiforme in Liver and Spleen
A case of a glioblastoma multiforme is presented. Craniotomy was performed with total resection of the right temporal tumor. Postoperatively, the patient received adjuvant radiotherapy, but 6 months after therapy he developed severe nausea and weight loss. Recurrence of an intracranial tumor in the...
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| Veröffentlicht in: | Digestion 2000-01, Vol.61 (3), p.219-222 |
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| container_title | Digestion |
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| creator | Widjaja, Adji Mix, Heiko Gölkel, Carsten Flemming, Peer Egensperger, Rupert Holstein, Andreas Rademaker, Jürgen Becker, Hartmut Hundt, Mathias Wagner, Siegfried Manns, Michael P. |
| description | A case of a glioblastoma multiforme is presented. Craniotomy was performed with total resection of the right temporal tumor. Postoperatively, the patient received adjuvant radiotherapy, but 6 months after therapy he developed severe nausea and weight loss. Recurrence of an intracranial tumor in the right temporal region with nodules in the liver and spleen were detected by CT scan. Fine-needle biopsies of the liver confirmed the diagnosis of a glioblastoma metastasis with characteristic immunohistochemical staining for glial fibrillary acidic protein. This rare case of an intracerebral glioblastoma metastasizing to liver and spleen was managed by systemic chemotherapy. |
| doi_str_mv | 10.1159/000007761 |
| format | Article |
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Craniotomy was performed with total resection of the right temporal tumor. Postoperatively, the patient received adjuvant radiotherapy, but 6 months after therapy he developed severe nausea and weight loss. Recurrence of an intracranial tumor in the right temporal region with nodules in the liver and spleen were detected by CT scan. Fine-needle biopsies of the liver confirmed the diagnosis of a glioblastoma metastasis with characteristic immunohistochemical staining for glial fibrillary acidic protein. This rare case of an intracerebral glioblastoma metastasizing to liver and spleen was managed by systemic chemotherapy.</description><identifier>ISSN: 0012-2823</identifier><identifier>EISSN: 1421-9867</identifier><identifier>DOI: 10.1159/000007761</identifier><identifier>PMID: 10773729</identifier><identifier>CODEN: DIGEBW</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Biological and medical sciences ; Brain Neoplasms - pathology ; Brain Neoplasms - therapy ; Case Report ; Gastroenterology. Liver. Pancreas. Abdomen ; Glioblastoma - pathology ; Glioblastoma - therapy ; Humans ; Liver Neoplasms - secondary ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Male ; Medical sciences ; Middle Aged ; Neoplasm Recurrence, Local ; Neurology ; Splenic Neoplasms - secondary ; Tumors ; Tumors of the nervous system. Phacomatoses</subject><ispartof>Digestion, 2000-01, Vol.61 (3), p.219-222</ispartof><rights>2000 S. 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Craniotomy was performed with total resection of the right temporal tumor. Postoperatively, the patient received adjuvant radiotherapy, but 6 months after therapy he developed severe nausea and weight loss. Recurrence of an intracranial tumor in the right temporal region with nodules in the liver and spleen were detected by CT scan. Fine-needle biopsies of the liver confirmed the diagnosis of a glioblastoma metastasis with characteristic immunohistochemical staining for glial fibrillary acidic protein. This rare case of an intracerebral glioblastoma metastasizing to liver and spleen was managed by systemic chemotherapy.</description><subject>Biological and medical sciences</subject><subject>Brain Neoplasms - pathology</subject><subject>Brain Neoplasms - therapy</subject><subject>Case Report</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Glioblastoma - pathology</subject><subject>Glioblastoma - therapy</subject><subject>Humans</subject><subject>Liver Neoplasms - secondary</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Neoplasm Recurrence, Local</subject><subject>Neurology</subject><subject>Splenic Neoplasms - secondary</subject><subject>Tumors</subject><subject>Tumors of the nervous system. 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| ispartof | Digestion, 2000-01, Vol.61 (3), p.219-222 |
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| subjects | Biological and medical sciences Brain Neoplasms - pathology Brain Neoplasms - therapy Case Report Gastroenterology. Liver. Pancreas. Abdomen Glioblastoma - pathology Glioblastoma - therapy Humans Liver Neoplasms - secondary Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Neoplasm Recurrence, Local Neurology Splenic Neoplasms - secondary Tumors Tumors of the nervous system. Phacomatoses |
| title | Uncommon Metastasis of a Glioblastoma Multiforme in Liver and Spleen |
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