Disulfide Connectivity in Cerebroside Sulfate Activator Is Not Necessary for Biological Activity or α-Helical Content but Is Necessary for Trypsin Resistance and Strong Ligand Binding

Cerebroside sulfate activator (CSAct) protein is exceptionally resistant to heat denaturation and proteolytic digestion. Although water soluble the protein binds membrane-associated lipids. Its biological role is thought to be to transfer certain lipids between membranes and to facilitate their cata...

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