Cellular localization, membrane distribution, and possible function of guanylyl cyclases A and 1 in collecting ducts of rat

Natriuretic peptides regulate Na+ and H(2)O transport in the cortical collecting duct (CCD). We have shown that natriuretic peptides have no effect on ion conductances or water transport of principal cells (PC) even though a cGMP-regulated K+ channel is located in the basolateral membrane of these c...

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Veröffentlicht in:	Cardiovascular research 2001-08, Vol.51 (3), p.553-561
Hauptverfasser:	HIRSCH, Jochen R, KRUHØFFER, Mogens, ADERMANN, Knut, HEITLAND, Aleksandra, MARONDE, Erik, MEYER, Markus, FORSSMANN, Wolf-Georg, HERTER, Peter, PLENZ, Gabriele, SCHLATTER, Eberhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atrial Natriuretic Factor - pharmacology Biological and medical sciences Cell Membrane - enzymology Diuretics - pharmacology Female Fundamental and applied biological sciences. Psychology Gene Expression Guanylate Cyclase - genetics Guanylate Cyclase - metabolism Guanylate Cyclase - physiology Hydrogen-Ion Concentration - drug effects Kidney Tubules, Collecting - enzymology Kidney Tubules, Collecting - physiology Male Peptide Fragments - pharmacology Rats Rats, Sprague-Dawley Rats, Wistar Receptors, Atrial Natriuretic Factor - genetics Receptors, Atrial Natriuretic Factor - metabolism Receptors, Atrial Natriuretic Factor - physiology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Vertebrates: urinary system
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