Neurosteroids and brain sexual differentiation

There is new evidence that the brain of developing songbirds can synthesize estradiol de novo. In males, this neurally derived estrogen might masculinize a connection within the neural song system. These results challenge traditional concepts about mechanisms of brain sexual differentiation and reve...

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Veröffentlicht in:Trends in neurosciences (Regular ed.) 2001-08, Vol.24 (8), p.429-431
Hauptverfasser: Schlinger, Barney A., Soma, Kiran K., London, Sarah E.
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container_title Trends in neurosciences (Regular ed.)
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creator Schlinger, Barney A.
Soma, Kiran K.
London, Sarah E.
description There is new evidence that the brain of developing songbirds can synthesize estradiol de novo. In males, this neurally derived estrogen might masculinize a connection within the neural song system. These results challenge traditional concepts about mechanisms of brain sexual differentiation and reveal a significant function for neurosteroids.
doi_str_mv 10.1016/S0166-2236(00)01855-5
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subjects Animals
Biological and medical sciences
Brain
Brain Chemistry - physiology
Estradiol
Estradiol - physiology
Female
Fundamental and applied biological sciences. Psychology
General aspects. Models. Methods
Male
Masculinization
Neurotransmitters
Sex Differentiation
Sex-steroid
Sexuality
Song System
Songbirds
Steroids
Telencephalon
Vertebrates: nervous system and sense organs
title Neurosteroids and brain sexual differentiation
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