Immunorestitution diseases in patients not infected with HIV

The aim of this study was to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalized patients over a 12-month period. In nine of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n = 6) or bone marrow engraftment (n = 3...

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Veröffentlicht in:European journal of clinical microbiology & infectious diseases 2001-06, Vol.20 (6), p.402-406
Hauptverfasser: CHENG, V. C. C, YUEN, K. Y, WONG, S. S. Y, WOO, P. C. Y, HO, P. L, LEE, R, CHAN, R. M. T
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container_end_page 406
container_issue 6
container_start_page 402
container_title European journal of clinical microbiology & infectious diseases
container_volume 20
creator CHENG, V. C. C
YUEN, K. Y
WONG, S. S. Y
WOO, P. C. Y
HO, P. L
LEE, R
CHAN, R. M. T
description The aim of this study was to assess the clinical spectrum of immunorestitution disease (IRD) in hospitalized patients over a 12-month period. In nine of 18 patients who presented with clinical deterioration during reduction or cessation of immunosuppressants (n = 6) or bone marrow engraftment (n = 3), IRD cases included the following infections: scabies infestation (n = 1); gastric strongyloidiasis (n = 1); hepatosplenic candidiasis (n = 1); methicillin-resistant Staphylococcus aureus abscess formation (n = 2); polyomavirus-related hemorrhagic cystitis (n = 3); and influenza A pneumonitis (n = 1). Immunopathological damage during withdrawal of immunosuppression is an incidental way to uncover an asymptomatic infectious disease. Serial monitoring of hematological and clinical profiles is essential in making a diagnosis of IRD.
doi_str_mv 10.1007/s100960100507
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ispartof European journal of clinical microbiology & infectious diseases, 2001-06, Vol.20 (6), p.402-406
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subjects Adult
Biological and medical sciences
Bone marrow
Bone Marrow Transplantation - immunology
Child
Diagnosis, Differential
Female
Humans
Immunocompromised Host
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Immunosuppressive Agents - administration & dosage
Infectious diseases
Lymphocyte Count
Male
Medical sciences
Opportunistic Infections - diagnosis
Opportunistic Infections - immunology
Opportunistic Infections - microbiology
Prospective Studies
title Immunorestitution diseases in patients not infected with HIV
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