Identification of N(omega)-carboxymethylarginine, a new advanced glycation endproduct in serum proteins of diabetic patients: possibility of a new marker of aging and diabetes

A new advanced glycation end product (AGE), N(omega)-carboxymethyl-arginine (CMA), was found in acid-soluble skin collagen of a newborn bovine prepared by in vitro glycation with 1 M glucose incubation at 37 degrees C for about 30 days [ 1 ]. CMA production was increased with incubation time in para...

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Veröffentlicht in:	Biochemical and biophysical research communications 2001-08, Vol.285 (5), p.1232-1236
Hauptverfasser:	Odani, H, Iijima, K, Nakata, M, Miyata, S, Kusunoki, H, Yasuda, Y, Hiki, Y, Irie, S, Maeda, K, Fujimoto, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - blood Arginine - analogs & derivatives Arginine - blood Biomarkers - blood Calibration Chromatography, Liquid Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - diagnosis Glycation End Products, Advanced - blood Humans Middle Aged Reproducibility of Results Spectrometry, Mass, Electrospray Ionization
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