Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients
Quantifying the functional consequences of illness in terms of quality of life can enhance our understanding of both mental and physical disorders. However, little is known about the quality of life among older inpatients vs. outpatients with schizophrenia. We present the results of health-related q...
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Veröffentlicht in: | Psychiatry research 2001-08, Vol.103 (1), p.69-78 |
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creator | Kasckow, John W Twamley, Elizabeth Mulchahey, James J Carroll, Brendan Sabai, Mya Strakowski, Stephen M Patterson, Thomas Jeste, Dilip V |
description | Quantifying the functional consequences of illness in terms of quality of life can enhance our understanding of both mental and physical disorders. However, little is known about the quality of life among older inpatients vs. outpatients with schizophrenia. We present the results of health-related quality of life assessments in 54 middle-aged and elderly long-term inpatients with schizophrenia and a demographically matched outpatient sample. Assessments were performed using the Quality of Well-Being (QWB) scale, along with standard measures of psychopathology and global cognitive impairment. Compared with outpatients, the inpatients had a significantly lower health-related quality of life, as measured by the QWB. In the inpatient and outpatient groups, higher levels of positive symptoms were associated with lower health-related quality of life. Health-related quality of life remained fairly stable among the inpatients who remained hospitalized over 6 months. In both inpatients and outpatients, baseline cognitive status and psychopathology predicted QWB scores at the 6-month follow-up. These findings further support the use of the QWB in severely mentally ill populations; implications for improving health-related quality of life among older patients with schizophrenia are discussed. |
doi_str_mv | 10.1016/S0165-1781(01)00260-8 |
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However, little is known about the quality of life among older inpatients vs. outpatients with schizophrenia. We present the results of health-related quality of life assessments in 54 middle-aged and elderly long-term inpatients with schizophrenia and a demographically matched outpatient sample. Assessments were performed using the Quality of Well-Being (QWB) scale, along with standard measures of psychopathology and global cognitive impairment. Compared with outpatients, the inpatients had a significantly lower health-related quality of life, as measured by the QWB. In the inpatient and outpatient groups, higher levels of positive symptoms were associated with lower health-related quality of life. Health-related quality of life remained fairly stable among the inpatients who remained hospitalized over 6 months. In both inpatients and outpatients, baseline cognitive status and psychopathology predicted QWB scores at the 6-month follow-up. These findings further support the use of the QWB in severely mentally ill populations; implications for improving health-related quality of life among older patients with schizophrenia are discussed.</description><identifier>ISSN: 0165-1781</identifier><identifier>EISSN: 1872-7123</identifier><identifier>DOI: 10.1016/S0165-1781(01)00260-8</identifier><identifier>PMID: 11472791</identifier><identifier>CODEN: PSRSDR</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Biological and medical sciences ; Chronic Disease ; Cognition ; Cognition Disorders - diagnosis ; Cognition Disorders - etiology ; Depression ; Female ; Follow-Up Studies ; Health Status ; Hospitalization ; Hospitals, Psychiatric ; Humans ; Institution therapy. Inpatient treatment ; Length of Stay ; Male ; Medical sciences ; Middle Aged ; Negative symptoms ; Neuropsychological Tests ; Personal Satisfaction ; Positive symptoms ; Psychology. Psychoanalysis. 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However, little is known about the quality of life among older inpatients vs. outpatients with schizophrenia. We present the results of health-related quality of life assessments in 54 middle-aged and elderly long-term inpatients with schizophrenia and a demographically matched outpatient sample. Assessments were performed using the Quality of Well-Being (QWB) scale, along with standard measures of psychopathology and global cognitive impairment. Compared with outpatients, the inpatients had a significantly lower health-related quality of life, as measured by the QWB. In the inpatient and outpatient groups, higher levels of positive symptoms were associated with lower health-related quality of life. Health-related quality of life remained fairly stable among the inpatients who remained hospitalized over 6 months. In both inpatients and outpatients, baseline cognitive status and psychopathology predicted QWB scores at the 6-month follow-up. These findings further support the use of the QWB in severely mentally ill populations; implications for improving health-related quality of life among older patients with schizophrenia are discussed.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Chronic Disease</subject><subject>Cognition</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognition Disorders - etiology</subject><subject>Depression</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health Status</subject><subject>Hospitalization</subject><subject>Hospitals, Psychiatric</subject><subject>Humans</subject><subject>Institution therapy. Inpatient treatment</subject><subject>Length of Stay</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Negative symptoms</subject><subject>Neuropsychological Tests</subject><subject>Personal Satisfaction</subject><subject>Positive symptoms</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychosis</subject><subject>Quality of Life</subject><subject>Schizophrenia - complications</subject><subject>Schizophrenia - rehabilitation</subject><subject>Severity of Illness Index</subject><subject>Treatments</subject><issn>0165-1781</issn><issn>1872-7123</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE2P1SAUhonRONfRn6BhYcy4qHJoKXQ2xkzUMZnEhbomlJ5aTFs6QJ3c2c0_l3qvHzsT4Cx43nPgIeQpsFfAoH79OR-iAKngjMFLxnjNCnWP7EBJXkjg5X2y-4OckEcxfmeZgqZ5SE4AKsllAztyd4lmTEMRcDQJO3q9mtGlPfU9vcFxLFp08zfqZmqH4GdnzTju6eDj4lIGb3NiMcnhnCK9cWmg0Q7u1i9DwNmZc2r9tJjgop8P15NJdsghv6bfucfkQW_GiE-O9ZR8ff_uy8VlcfXpw8eLt1eFrSqeCuC8U4KD6G0j6lIi57K1XNmet0oYo3pe1hxQWdM1orMCZNVhWYu2VtsuT8mLQ98l-OsVY9KTizb_0czo16glsKqBpsqgOIA2-BgD9noJbjJhr4Hpzb3-5V5vYjXLa3OvtwHPjgPWdsLub-ooOwPPj4CJWWQfzGxd_Ke7lGVTZ-zNAcNs44fDoKPNpix2LqBNuvPuPy_5CRUCo0o</recordid><startdate>20010805</startdate><enddate>20010805</enddate><creator>Kasckow, John W</creator><creator>Twamley, Elizabeth</creator><creator>Mulchahey, James J</creator><creator>Carroll, Brendan</creator><creator>Sabai, Mya</creator><creator>Strakowski, Stephen M</creator><creator>Patterson, Thomas</creator><creator>Jeste, Dilip V</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010805</creationdate><title>Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients</title><author>Kasckow, John W ; Twamley, Elizabeth ; Mulchahey, James J ; Carroll, Brendan ; Sabai, Mya ; Strakowski, Stephen M ; Patterson, Thomas ; Jeste, Dilip V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-122d85215fc95637e227bc28cf2b85aa8f23621e8cad95dc5174de365b685b683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Chronic Disease</topic><topic>Cognition</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognition Disorders - etiology</topic><topic>Depression</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health Status</topic><topic>Hospitalization</topic><topic>Hospitals, Psychiatric</topic><topic>Humans</topic><topic>Institution therapy. 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subjects | Adult Biological and medical sciences Chronic Disease Cognition Cognition Disorders - diagnosis Cognition Disorders - etiology Depression Female Follow-Up Studies Health Status Hospitalization Hospitals, Psychiatric Humans Institution therapy. Inpatient treatment Length of Stay Male Medical sciences Middle Aged Negative symptoms Neuropsychological Tests Personal Satisfaction Positive symptoms Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychosis Quality of Life Schizophrenia - complications Schizophrenia - rehabilitation Severity of Illness Index Treatments |
title | Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients |
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