HETEROZYGOSITY-FITNESS CORRELATIONS IN RAINBOW TROUT: EFFECTS OF ALLOZYME LOCI OR ASSOCIATIVE OVERDOMINANCE?
Previous studies with rainbow trout (Oncorhynchus mykiss) have shown that increased heterozygosity at allozyme loci is correlated with several phenotypic traits associated with fitness. We expected to find a similar effect of heterozygosity at other nuclear loci if these associations are due to loci...
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| Veröffentlicht in: | Evolution 2001-06, Vol.55 (6), p.1180-1187, Article 1180 |
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| creator | Thelen, G. C Allendorf, F. W |
| description | Previous studies with rainbow trout (Oncorhynchus mykiss) have shown that increased heterozygosity at allozyme loci is correlated with several phenotypic traits associated with fitness. We expected to find a similar effect of heterozygosity at other nuclear loci if these associations are due to loci in linkage disequilibrium with the allozyme loci (i.e., associative overdominance), rather than the allozymes themselves. We examined the association between multiple locus heterozygosity and condition factor at 10 allozyme and 10 microsatellite loci. Individuals that were more heterozygous at allozyme loci had significantly greater condition factor in two hatchery cohorts of rainbow trout (1996 P = 0.006; 1997 P < 0.001). In contrast, there was no evidence at microsatellite loci that increased heterozygosity was associated with greater condition factor. Our results suggest that the observed relationship between heterozygosity at allozyme loci and condition factor in rainbow trout appears to be due to the allozyme loci themselves, rather than associative overdominance. We cannot, however, rule out that differences in the mutation process between allozymes and microsatellites may be responsible for these observations. Regardless of the underlying mechanism, these results support the view that allozymes and microsatellites are differentially affected by natural selection. Corresponding Editor: M. Douglas |
| doi_str_mv | 10.1554/0014-3820(2001)055[1180:HFCIRT]2.0.CO;2 |
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Our results suggest that the observed relationship between heterozygosity at allozyme loci and condition factor in rainbow trout appears to be due to the allozyme loci themselves, rather than associative overdominance. We cannot, however, rule out that differences in the mutation process between allozymes and microsatellites may be responsible for these observations. Regardless of the underlying mechanism, these results support the view that allozymes and microsatellites are differentially affected by natural selection. Corresponding Editor: M. 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C</creatorcontrib><creatorcontrib>Allendorf, F. W</creatorcontrib><title>HETEROZYGOSITY-FITNESS CORRELATIONS IN RAINBOW TROUT: EFFECTS OF ALLOZYME LOCI OR ASSOCIATIVE OVERDOMINANCE?</title><title>Evolution</title><addtitle>Evolution</addtitle><description>Previous studies with rainbow trout (Oncorhynchus mykiss) have shown that increased heterozygosity at allozyme loci is correlated with several phenotypic traits associated with fitness. We expected to find a similar effect of heterozygosity at other nuclear loci if these associations are due to loci in linkage disequilibrium with the allozyme loci (i.e., associative overdominance), rather than the allozymes themselves. We examined the association between multiple locus heterozygosity and condition factor at 10 allozyme and 10 microsatellite loci. Individuals that were more heterozygous at allozyme loci had significantly greater condition factor in two hatchery cohorts of rainbow trout (1996 P = 0.006; 1997 P < 0.001). 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C</au><au>Allendorf, F. W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HETEROZYGOSITY-FITNESS CORRELATIONS IN RAINBOW TROUT: EFFECTS OF ALLOZYME LOCI OR ASSOCIATIVE OVERDOMINANCE?</atitle><jtitle>Evolution</jtitle><addtitle>Evolution</addtitle><date>2001-06-01</date><risdate>2001</risdate><volume>55</volume><issue>6</issue><spage>1180</spage><epage>1187</epage><pages>1180-1187</pages><artnum>1180</artnum><issn>0014-3820</issn><eissn>1558-5646</eissn><abstract>Previous studies with rainbow trout (Oncorhynchus mykiss) have shown that increased heterozygosity at allozyme loci is correlated with several phenotypic traits associated with fitness. We expected to find a similar effect of heterozygosity at other nuclear loci if these associations are due to loci in linkage disequilibrium with the allozyme loci (i.e., associative overdominance), rather than the allozymes themselves. We examined the association between multiple locus heterozygosity and condition factor at 10 allozyme and 10 microsatellite loci. Individuals that were more heterozygous at allozyme loci had significantly greater condition factor in two hatchery cohorts of rainbow trout (1996 P = 0.006; 1997 P < 0.001). In contrast, there was no evidence at microsatellite loci that increased heterozygosity was associated with greater condition factor. Our results suggest that the observed relationship between heterozygosity at allozyme loci and condition factor in rainbow trout appears to be due to the allozyme loci themselves, rather than associative overdominance. We cannot, however, rule out that differences in the mutation process between allozymes and microsatellites may be responsible for these observations. Regardless of the underlying mechanism, these results support the view that allozymes and microsatellites are differentially affected by natural selection. Corresponding Editor: M. Douglas</abstract><cop>United States</cop><pub>Society for the Study of Evolution</pub><pmid>11475053</pmid><doi>10.1554/0014-3820(2001)055[1180:HFCIRT]2.0.CO;2</doi><tpages>8</tpages></addata></record> |
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| ispartof | Evolution, 2001-06, Vol.55 (6), p.1180-1187, Article 1180 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; BioOne Complete; Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Alleles Allozymes Animals associative overdominance Ecological competition Electrophoresis, Starch Gel Enzymes Evolutionary genetics Fish fitness Fresh Water Genetic Carrier Screening Genetic loci Genetic Variation Genetics Genotype heterozygosity Heterozygotes Homozygotes Isoenzymes - genetics Microsatellite Repeats - genetics Microsatellites Montana Mutation Oncorhynchus mykiss Oncorhynchus mykiss - genetics Overdominance Regression Analysis REGULAR ARTICLES Trout |
| title | HETEROZYGOSITY-FITNESS CORRELATIONS IN RAINBOW TROUT: EFFECTS OF ALLOZYME LOCI OR ASSOCIATIVE OVERDOMINANCE? |
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