Role of platelet-derived growth factor in allograft vasculopathy

To test the hypothesis that platelet-derived growth factor (PDGF) accelerates the formation of allograft vascular disease. Allograft vasculopathy, characterized by myointimal hyperplasia of the coronary arteries in the transplanted heart, is the most common cause of late graft failure and death in h...

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Veröffentlicht in:	Annals of surgery 2000-05, Vol.231 (5), p.682-688
Hauptverfasser:	Mancini, M C, Evans, J T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Coronary Disease - etiology Female Graft Rejection - pathology Heart Transplantation - pathology Hyperplasia - pathology Male Platelet-Derived Growth Factor - pharmacology Platelet-Derived Growth Factor - physiology Rats Rats, Inbred Strains Tunica Intima - pathology
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