Endothelial cell activation by pore-forming structures: pivotal role for interleukin-1alpha

Interaction of complement with endothelial cells (ECs) underlies the development of inflammation and coagulation in disease. Assembly of the membrane attack complex (MAC) of complement on EC membrane, like stimulation with cytokines, upregulates tissue factor and cyclooxygenase-2 but does so via the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2000-04, Vol.101 (15), p.1867-1873
Hauptverfasser:	Saadi, S, Holzknecht, R A, Patte, C P, Platt, J L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Complement Activation - physiology Complement Membrane Attack Complex - metabolism E-Selectin - metabolism Endothelium, Vascular - cytology Interleukin-1 - metabolism Kinetics Membrane Proteins - metabolism RNA, Messenger - metabolism Swine Up-Regulation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!