Feature selection for DNA methylation based cancer classification

Molecular portraits, such as mRNA expression or DNA methylation patterns, have been shown to be strongly correlated with phenotypical parameters. These molecular patterns can be revealed routinely on a genomic scale. However, class prediction based on these patterns is an under-determined problem, d...

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Veröffentlicht in:	Bioinformatics 2001-06, Vol.17 (suppl-1), p.S157-S164
Hauptverfasser:	Model, Fabian, Adorján, Péter, Olek, Alexander, Piepenbrock, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Computational Biology CpG Islands DNA Methylation DNA, Neoplasm - chemistry Humans Leukemia, Myeloid, Acute - metabolism Neoplasms - chemistry Neoplasms - classification Oligonucleotide Array Sequence Analysis - statistics & numerical data Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism Principal Component Analysis
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