Heat-inducible vectors for use in gene therapy

The objectives of this study were to quantity and compare the activities of a minimal heat shock (HS) promoter and other promoters used in gene therapy applications, and to identify strategies to amplify the heat inducibility of therapeutic genes. Human tumour cells were transiently or stably transf...

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Veröffentlicht in:	International journal of hyperthermia 2000, Vol.16 (2), p.171-181
Hauptverfasser:	Gerner, E. W., Hersh, E. M., Pennington, M., Tsang, T. C., Harris, D., Vasanwala, F., Brailey, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences Biotechnology Fundamental and applied biological sciences. Psychology Gene therapy Genes, tat Genetic Therapy Genetic Vectors Green Fluorescent Proteins Health. Pharmaceutical industry Heat Shock Promoter Gene Expression HIV-1 - genetics HSP70 Heat-Shock Proteins - genetics Humans Hyperthermia, Induced Industrial applications and implications. Economical aspects Interleukin-2 - genetics Luminescent Proteins - genetics Promoter Regions, Genetic Tumor Cells, Cultured
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