Clinical Features of Nipah Virus Encephalitis among Pig Farmers in Malaysia

Between September 1998 and June 1999, there was an outbreak of febrile encephalitis in several pig-farming villages in Malaysia. More than 200 patients were admitted to hospitals nationwide, many of whom died. 1 – 3 The pig-farming industry was disrupted by the culling of many pigs to control the ou...

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Veröffentlicht in:The New England journal of medicine 2000-04, Vol.342 (17), p.1229-1235
Hauptverfasser: Goh, Khean Jin, Tan, Patrick Seow Koon, Tan, Chong Tin, Chew, Nee Kong, Kamarulzaman, Adeeba, Sarji, Sazilah Ahmad, Wong, Kum Thong, Abdullah, Basri Johan Jeet, Chua, Kaw Bing, Lam, Sai Kit
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container_end_page 1235
container_issue 17
container_start_page 1229
container_title The New England journal of medicine
container_volume 342
creator Goh, Khean Jin
Tan, Patrick Seow Koon
Tan, Chong Tin
Chew, Nee Kong
Kamarulzaman, Adeeba
Sarji, Sazilah Ahmad
Wong, Kum Thong
Abdullah, Basri Johan Jeet
Chua, Kaw Bing
Lam, Sai Kit
description Between September 1998 and June 1999, there was an outbreak of febrile encephalitis in several pig-farming villages in Malaysia. More than 200 patients were admitted to hospitals nationwide, many of whom died. 1 – 3 The pig-farming industry was disrupted by the culling of many pigs to control the outbreak and the closing of farms. Several abattoir workers in neighboring Singapore were also affected. 4 , 5 Japanese encephalitis, a viral encephalitis associated with pigs that is endemic in Southeast Asia, was initially suspected, but clinical and epidemiologic features suggested that a different disease was responsible. The isolation of a new paramyxovirus, subsequently named . . .
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subjects Adult
Animal Husbandry
Animals
Antibodies, Viral - blood
Antibodies, Viral - cerebrospinal fluid
Cerebrospinal Fluid - chemistry
Cerebrospinal Fluid - immunology
Disease Outbreaks - statistics & numerical data
Electroencephalography
Encephalitis
Encephalitis, Viral - epidemiology
Encephalitis, Viral - mortality
Encephalitis, Viral - physiopathology
Encephalitis, Viral - virology
Female
Hogs
Humans
Logistic Models
Magnetic Resonance Imaging
Malaysia
Malaysia - epidemiology
Male
Nervous System Diseases - etiology
Nipah virus
NMR
Nuclear magnetic resonance
Paramyxoviridae Infections - complications
Paramyxoviridae Infections - epidemiology
Paramyxoviridae Infections - mortality
Paramyxoviridae Infections - physiopathology
Paramyxovirinae - immunology
pigs
Recurrence
Swine
title Clinical Features of Nipah Virus Encephalitis among Pig Farmers in Malaysia
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