3,5,3'-triiodothyronine deprivation affects phenotype and intracellular [Ca2+]i of human cardiomyocytes in culture

A decrease in plasma T3 concentration is a frequent finding in patients with heart failure. However, the role of this 'low T3 syndrome' on disease evolution has never been clarified. As phenotypic and functional cardiomyocyte impairments are alterations that correlate with the failing myoc...

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Veröffentlicht in:	Cardiovascular research 2001-08, Vol.51 (2), p.322-330
Hauptverfasser:	FORINI, Francesca, PAOLICCHI, Aldo, PIZZORUSSO, Tommaso, RATTO, Gian Michele, SAVIOZZI, Michela, VANINI, Vittorio, IERVASI, Giorgio
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western - methods Calcium - analysis Calcium - metabolism Cell Culture Techniques - methods Child, Preschool Female Fundamental and applied biological sciences. Psychology Heart Humans Immunohistochemistry - methods Indoles - pharmacology Intracellular Fluid - metabolism Male Microscopy, Fluorescence Myocardium - cytology Myocardium - metabolism Phenotype Thyroxine - deficiency Triiodothyronine - deficiency Vertebrates: cardiovascular system
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