CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: Accuracy in the detection of large vessel thrombus
The purpose of this work was to evaluate the accuracy of CT angiography (CTA) for the detection of large vessel intracranial thrombus in clinically suspected hyperacute (
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| Veröffentlicht in: | Journal of computer assisted tomography 2001-07, Vol.25 (4), p.520-528 |
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| container_title | Journal of computer assisted tomography |
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| creator | LEV, Michael H FARKAS, Jeffrey GONZALEZ, R. Gilberto RODRIGUEZ, Victor R SCHWAMM, Lee H HUNTER, George J PUTMAN, Christopher M RORDORF, Guy A BUONANNO, Ferdinando S BUDZIK, Ronald KOROSHETZ, Walter J |
| description | The purpose of this work was to evaluate the accuracy of CT angiography (CTA) for the detection of large vessel intracranial thrombus in clinically suspected hyperacute ( |
| doi_str_mv | 10.1097/00004728-200107000-00003 |
| format | Article |
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Forty-four consecutive intraarterial thrombolysis candidates underwent noncontrast CT followed immediately by CTA. Axial source and two-dimensional collapsed maximum intensity projection reformatted CTA images were rated for the presence or absence of large vessel occlusion. Five hundred seventy-two circle-of-Willis vessels were reviewed; arteriographic correlation was available for 224 of these.
Sensitivity and specificity for the detection of large vessel occlusion were 98.4 and 98.1%; accuracy, calculated using receiver operating characteristic analysis, was 99%. Mean time for acquisition, reconstruction, and analysis of CTA images was approximately 15 min.
CTA is highly accurate for the detection and exclusion of large vessel intracranial occlusion and may therefore be valuable in the rapid triage of hyperacute stroke patients to intraarterial thrombolytic treatment.</description><identifier>ISSN: 0363-8715</identifier><identifier>EISSN: 1532-3145</identifier><identifier>DOI: 10.1097/00004728-200107000-00003</identifier><identifier>PMID: 11473180</identifier><identifier>CODEN: JCATD5</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Cardiovascular system ; Cerebral Angiography - methods ; Female ; Humans ; Intracranial Thrombosis - diagnostic imaging ; Intracranial Thrombosis - pathology ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Retrospective Studies ; Sensitivity and Specificity ; Stroke - diagnosis ; Stroke - pathology ; Thrombolytic Therapy ; Tomography, X-Ray Computed - methods</subject><ispartof>Journal of computer assisted tomography, 2001-07, Vol.25 (4), p.520-528</ispartof><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c340t-fb18b01b0917a7c2163a21b5954f3728ad7ef90ec243437ffee659301992eef13</citedby><cites>FETCH-LOGICAL-c340t-fb18b01b0917a7c2163a21b5954f3728ad7ef90ec243437ffee659301992eef13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1099310$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11473180$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEV, Michael H</creatorcontrib><creatorcontrib>FARKAS, Jeffrey</creatorcontrib><creatorcontrib>GONZALEZ, R. Gilberto</creatorcontrib><creatorcontrib>RODRIGUEZ, Victor R</creatorcontrib><creatorcontrib>SCHWAMM, Lee H</creatorcontrib><creatorcontrib>HUNTER, George J</creatorcontrib><creatorcontrib>PUTMAN, Christopher M</creatorcontrib><creatorcontrib>RORDORF, Guy A</creatorcontrib><creatorcontrib>BUONANNO, Ferdinando S</creatorcontrib><creatorcontrib>BUDZIK, Ronald</creatorcontrib><creatorcontrib>KOROSHETZ, Walter J</creatorcontrib><title>CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: Accuracy in the detection of large vessel thrombus</title><title>Journal of computer assisted tomography</title><addtitle>J Comput Assist Tomogr</addtitle><description>The purpose of this work was to evaluate the accuracy of CT angiography (CTA) for the detection of large vessel intracranial thrombus in clinically suspected hyperacute (<6 h) stroke patients.
Forty-four consecutive intraarterial thrombolysis candidates underwent noncontrast CT followed immediately by CTA. Axial source and two-dimensional collapsed maximum intensity projection reformatted CTA images were rated for the presence or absence of large vessel occlusion. Five hundred seventy-two circle-of-Willis vessels were reviewed; arteriographic correlation was available for 224 of these.
Sensitivity and specificity for the detection of large vessel occlusion were 98.4 and 98.1%; accuracy, calculated using receiver operating characteristic analysis, was 99%. Mean time for acquisition, reconstruction, and analysis of CTA images was approximately 15 min.
CTA is highly accurate for the detection and exclusion of large vessel intracranial occlusion and may therefore be valuable in the rapid triage of hyperacute stroke patients to intraarterial thrombolytic treatment.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Cerebral Angiography - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Thrombosis - diagnostic imaging</subject><subject>Intracranial Thrombosis - pathology</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Stroke - diagnosis</subject><subject>Stroke - pathology</subject><subject>Thrombolytic Therapy</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>0363-8715</issn><issn>1532-3145</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkU9v1DAQxS0EotvCV0A-IG4pnkyyjrlVK_5JlbiUczTxjncN2TjYDmg_CV8XL90WfLFm9H7vWX5CSFDXoIx-q8ppdN1VtVKgdJmq0wqfiBW0WFcITftUrBSuseo0tBfiMqVvRasRm-fiAqDRCJ1aid-bO0nTzoddpHl_lH6Sec-yDH4rc_S0YxmcnCl7nnKSv3zey_1x5kh2ySxTjuE7yxwKmSNRzFygsZjEcBjCeEw-vZM31i4FeLTfcmabfZhO3iPFEvKTU-IHbkkvxDNHY-KX5_tKfP3w_m7zqbr98vHz5ua2stioXLkBukHBoAxo0raGNVINQ2vaxmH5INpqdkaxrRtsUDvHvG4NKjCmZnaAV-LNve8cw4-FU-4PPlkeR5o4LKnXoNDURhdhdy-0MaQU2fVz9AeKxx5Ufyqlfyilfyzl7woL-uqcsQwH3v4Dzy0UweuzgJKl0UWarE__BRiD5R1_ABf6lvg</recordid><startdate>20010701</startdate><enddate>20010701</enddate><creator>LEV, Michael H</creator><creator>FARKAS, Jeffrey</creator><creator>GONZALEZ, R. Gilberto</creator><creator>RODRIGUEZ, Victor R</creator><creator>SCHWAMM, Lee H</creator><creator>HUNTER, George J</creator><creator>PUTMAN, Christopher M</creator><creator>RORDORF, Guy A</creator><creator>BUONANNO, Ferdinando S</creator><creator>BUDZIK, Ronald</creator><creator>KOROSHETZ, Walter J</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20010701</creationdate><title>CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: Accuracy in the detection of large vessel thrombus</title><author>LEV, Michael H ; FARKAS, Jeffrey ; GONZALEZ, R. Gilberto ; RODRIGUEZ, Victor R ; SCHWAMM, Lee H ; HUNTER, George J ; PUTMAN, Christopher M ; RORDORF, Guy A ; BUONANNO, Ferdinando S ; BUDZIK, Ronald ; KOROSHETZ, Walter J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c340t-fb18b01b0917a7c2163a21b5954f3728ad7ef90ec243437ffee659301992eef13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular system</topic><topic>Cerebral Angiography - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Intracranial Thrombosis - diagnostic imaging</topic><topic>Intracranial Thrombosis - pathology</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Stroke - diagnosis</topic><topic>Stroke - pathology</topic><topic>Thrombolytic Therapy</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEV, Michael H</creatorcontrib><creatorcontrib>FARKAS, Jeffrey</creatorcontrib><creatorcontrib>GONZALEZ, R. Gilberto</creatorcontrib><creatorcontrib>RODRIGUEZ, Victor R</creatorcontrib><creatorcontrib>SCHWAMM, Lee H</creatorcontrib><creatorcontrib>HUNTER, George J</creatorcontrib><creatorcontrib>PUTMAN, Christopher M</creatorcontrib><creatorcontrib>RORDORF, Guy A</creatorcontrib><creatorcontrib>BUONANNO, Ferdinando S</creatorcontrib><creatorcontrib>BUDZIK, Ronald</creatorcontrib><creatorcontrib>KOROSHETZ, Walter J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of computer assisted tomography</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LEV, Michael H</au><au>FARKAS, Jeffrey</au><au>GONZALEZ, R. Gilberto</au><au>RODRIGUEZ, Victor R</au><au>SCHWAMM, Lee H</au><au>HUNTER, George J</au><au>PUTMAN, Christopher M</au><au>RORDORF, Guy A</au><au>BUONANNO, Ferdinando S</au><au>BUDZIK, Ronald</au><au>KOROSHETZ, Walter J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: Accuracy in the detection of large vessel thrombus</atitle><jtitle>Journal of computer assisted tomography</jtitle><addtitle>J Comput Assist Tomogr</addtitle><date>2001-07-01</date><risdate>2001</risdate><volume>25</volume><issue>4</issue><spage>520</spage><epage>528</epage><pages>520-528</pages><issn>0363-8715</issn><eissn>1532-3145</eissn><coden>JCATD5</coden><abstract>The purpose of this work was to evaluate the accuracy of CT angiography (CTA) for the detection of large vessel intracranial thrombus in clinically suspected hyperacute (<6 h) stroke patients.
Forty-four consecutive intraarterial thrombolysis candidates underwent noncontrast CT followed immediately by CTA. Axial source and two-dimensional collapsed maximum intensity projection reformatted CTA images were rated for the presence or absence of large vessel occlusion. Five hundred seventy-two circle-of-Willis vessels were reviewed; arteriographic correlation was available for 224 of these.
Sensitivity and specificity for the detection of large vessel occlusion were 98.4 and 98.1%; accuracy, calculated using receiver operating characteristic analysis, was 99%. Mean time for acquisition, reconstruction, and analysis of CTA images was approximately 15 min.
CTA is highly accurate for the detection and exclusion of large vessel intracranial occlusion and may therefore be valuable in the rapid triage of hyperacute stroke patients to intraarterial thrombolytic treatment.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>11473180</pmid><doi>10.1097/00004728-200107000-00003</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0363-8715 |
| ispartof | Journal of computer assisted tomography, 2001-07, Vol.25 (4), p.520-528 |
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| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Cardiovascular system Cerebral Angiography - methods Female Humans Intracranial Thrombosis - diagnostic imaging Intracranial Thrombosis - pathology Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Radiodiagnosis. Nmr imagery. Nmr spectrometry Retrospective Studies Sensitivity and Specificity Stroke - diagnosis Stroke - pathology Thrombolytic Therapy Tomography, X-Ray Computed - methods |
| title | CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: Accuracy in the detection of large vessel thrombus |
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