Zinc causes a shift toward citrate at equilibrium of the m-aconitase reaction of prostate mitochondria

Prostate secretory epithelial cells have the unique function and capability of accumulating and secreting extraordinarily high levels of citrate. To achieve this, these cells possess a uniquely limiting mitochondrial (m)-aconitase activity that minimizes the oxidation of citrate via the Krebs cycle....

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Veröffentlicht in:	Journal of inorganic biochemistry 2000-01, Vol.78 (2), p.161-165
Hauptverfasser:	Costello, Leslie C, Franklin, Renty B, Liu, Y, Kennedy, M.Claire
Format:	Artikel
Sprache:	eng
Schlagworte:	Aconitate Hydratase - metabolism Animals Citrate Male Mitochondria - enzymology Mitochondria - metabolism Mitochondrial aconitase Prostate - enzymology Prostate - metabolism Prostate - ultrastructure Prostate cells Rats Rats, Wistar Zinc Zinc - metabolism
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