Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats

Interleukin-10 (IL-10) and interleukin-4 (IL-4), two Th2-derived cytokines, are molecules with anti-inflammatory and immunodeviating properties whose direct expression in allografts may prolong graft survival. Recombinant adenoviruses represent efficient vectors for gene transfer in quiescent cells...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Gene therapy 2000-03, Vol.7 (6), p.505-510
Hauptverfasser:	DAVID, A, CHETRITT, J, GUILLOT, C, TESSON, L, HESLAN, J.-M, CUTURI, M.-C, SOULILLOU, J.-P, ANEGON, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Adenovirus Adenoviruses Allografts Animals beta-Galactosidase - genetics Biological and medical sciences Biopsy Biotechnology CD8 antigen Cytokines Expression vectors Fundamental and applied biological sciences. Psychology Gene Expression Gene therapy Gene transfer Gene Transfer Techniques Genetic Therapy - methods Genetic Vectors - administration & dosage Graft Rejection - immunology Graft Rejection - prevention & control Health. Pharmaceutical industry Heart transplantation Heart Transplantation - immunology Immune response Immunohistochemistry Immunotherapy - methods Industrial applications and implications. Economical aspects Inflammation Interleukin 10 Interleukin 4 Interleukin-10 - genetics Interleukin-10 - therapeutic use Interleukin-4 - genetics Leukocytes Lymphocytes T Rats Transforming growth factor-b1 Transplantation, Homologous β-Galactosidase γ-Interferon
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!