The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM)

Mechanical hyperventilation of acidemic patients with acute lung injury (ALI) requires the use of high volumes and pressures that may worsen lung injury. However, permissive hypercapnia in the presence of shock, metabolic acidosis, and multi-organ system dysfunction may compromise normal cellular fu...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2000-04, Vol.161 (4), p.1149-1153
Hauptverfasser:	KALLET, R. H, JASMER, R. M, LUCE, J. M, LIN, L. H, MARKS, J. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis - drug therapy Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Emergency and intensive respiratory care Female Humans Intensive care medicine Male Medical sciences Middle Aged Respiration, Artificial Respiratory Distress Syndrome, Adult - complications Respiratory Distress Syndrome, Adult - drug therapy Respiratory Distress Syndrome, Adult - therapy Sodium Bicarbonate - therapeutic use Tromethamine - therapeutic use
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