Predominance of one T-cell antigen receptor BV haplotype in African populations

The human T-cell antigen receptor (TCR) is the counter-receptor for the HLA/peptide complex displayed on the surface of antigen-presenting cells. It confers antigen specificity on T lymphocytes and therefore plays a central role in pathogen recognition and host response. The most frequently used for...

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Veröffentlicht in:	Immunogenetics (New York) 2000-03, Vol.51 (3), p.231-237
Hauptverfasser:	Craddock, T P, Zumla, A M, Ollier, W E, Chintu, C Z, Muyinda, G P, Lancaster, F C, Boylston, A W
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa African Continental Ancestry Group - genetics Alleles Cameroon European Continental Ancestry Group - genetics Gene Frequency Genetic Variation Haplotypes histocompatibility antigen HLA Humans Linkage Disequilibrium Nigeria Phenotype Receptors, Antigen, T-Cell, alpha-beta - classification Receptors, Antigen, T-Cell, alpha-beta - genetics TCRBV gene Zambia
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