The effect of nitric oxide and peroxynitrite on rabbit cavernosal smooth muscle relaxation

Nitric oxide (NO) mediates penile erection by inducing cavernosal smooth muscle relaxation. Superoxide anion (O2-) can influence the activity of NO by reacting with it to produce peroxynitrite (PN). This is a highly reactive species that is known to attack a variety of biological targets. It is far...

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Veröffentlicht in:	World journal of urology 2001-06, Vol.19 (3), p.220-224
Hauptverfasser:	KHAN, Masood A, THOMPSON, Cecil S, MUMTAZ, Faiz H, MIKHAILIDIS, Dimitri P, MORGAN, Robert J, BRUCKDORFER, Richard K, NASEEM, Khaleed M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Male Mammalian male genital system Models, Animal Morphology. Physiology Muscle Relaxation - drug effects Nitric oxide Nitric Oxide - pharmacology Penile Erection - physiology Penis - drug effects Penis - physiology Peroxynitrous Acid - pharmacology Proteins Rabbits Smooth muscle Vasodilator Agents - pharmacology Vertebrates: reproduction
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