Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation

Lack of evidence of blood pressure-independent protection by renin-angiotensin system blockade after renal ablation. The superiority of renin-angiotensin system (RAS) blockade in providing renoprotection has been attributed to class-specific blood pressure “(BP)-independent” mechanisms. However, the...

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Veröffentlicht in:	Kidney international 2000-04, Vol.57 (4), p.1651-1661
Hauptverfasser:	Bidani, Anil K., Griffin, Karen A., Bakris, George, Picken, Maria M.
Format:	Artikel
Sprache:	eng
Schlagworte:	angiotensin-converting enzyme inhibitor Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Antihypertensive Agents - pharmacology Arterial hypertension. Arterial hypotension AT1 receptor antagonist Benzazepines - pharmacology Biological and medical sciences Blood and lymphatic vessels Blood Pressure - physiology Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology glomerulosclerosis Glomerulosclerosis, Focal Segmental - physiopathology hypertension Kidney - physiology Losartan - pharmacology Male Medical sciences Nephrectomy progressive renal disease Radio Waves Rats Rats, Sprague-Dawley Renin-Angiotensin System - drug effects Renin-Angiotensin System - physiology Telemetry
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