Cationic Phosphonolipids as Nonviral Vectors: In Vitro and in Vivo Applications

Since the development of the concept of gene therapy using cationic lipids as nonviral vectors by Felgner's group in 1987, numerous molecules have been synthesized. Such vectors were first proposed to avoid viral vector‐induced drawbacks. But, it quickly became clear that a thorough knowledge o...

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Veröffentlicht in:Journal of pharmaceutical sciences 2000-05, Vol.89 (5), p.629-638
Hauptverfasser: Delépine, P., Guillaume, C., Floch, V., Loisel, S., Yaouanc, J.‐J., Clément, J.‐C., Des Abbayes, H., Férec, C.
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Sprache:eng
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