Micellar electrokinetic capillary chromatography for the determination of Viagra and its metabolite (UK-103,320) in human serum

Micellar electrokinetic capillary chromatography (MEKC) was investigated for the determination of Viagra (sildenafil citrate, SC) and its metabolite (UK‐103,320) in human serum in a concentration range of clinical interest. For MEKC, human serum samples spiked with SC and UK were obtained directly a...

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Veröffentlicht in:	Electrophoresis 2001-06, Vol.22 (10), p.2004-2009
Hauptverfasser:	Nevado, Juan J. Berzas, Flores, Juana Rodríguez, Peñalvo, Gregorio Castañeda, Fariñas, Nuria Rodríguez
Format:	Artikel
Sprache:	eng
Schlagworte:	Electrophoresis, Capillary - methods Electrophoresis, Capillary - statistics & numerical data Human serum Humans Male Micellar electrokinetic capillary chromatography Micelles Osmolar Concentration Phosphodiesterase Inhibitors - blood Phosphodiesterase Inhibitors - metabolism Piperazines - blood Piperazines - metabolism Purines Pyrimidinones - blood Pyrimidinones - metabolism Sildenafil Citrate Sildenafil citrate (Viagra) Sildenafil metabolite (UK-103 Sildenafil metabolite (UK‐103,320) Sodium Dodecyl Sulfate Sulfones Temperature
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