XIAP: apoptotic brake and promising therapeutic target

The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the newly discovered family of intrinsic inhibitors of apoptosis (IAP) proteins. IAPs block cell death both in vitro and in vivo by virtue of inhibition of distinct caspases. Although other proteins have been identified which inhibit upst...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Apoptosis (London) 2001-08, Vol.6 (4), p.253-261
Hauptverfasser:	Holcik, M, Gibson, H, Korneluk, R G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Caspases - metabolism Forecasting Gene Expression Regulation Genetic Therapy Humans Irradiation Mortality Neoplasms - therapy Protein synthesis Proteins Proteins - genetics Proteins - physiology Proteins - therapeutic use Signal Transduction X-Linked Inhibitor of Apoptosis Protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!