Effect of bilateral subthalamic nucleus stimulation on gait in Parkinson's disease

The fundamental disturbance of the parkinsonian gait is the reduction in walking velocity. This is mainly due to reduction in stride length, while cadence (steps/min) is slightly enhanced. Treatment with l-dopa increases stride length while cadence is unchanged. Chronic stimulation of the thalamus h...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2001-08, Vol.124 (8), p.1590-1600
Hauptverfasser:	Faist, M., Xie, J., Kurz, D., Berger, W., Maurer, C., Pollak, P., Lücking, C. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiparkinson Agents - pharmacology Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Electric Stimulation Female gait analysis gait disorders Gait Disorders, Neurologic - therapy GPi = internal globus pallidus Humans Levodopa - pharmacology Male Medical sciences Middle Aged movement disorders Neurology Parkinson Disease - complications Parkinson Disease - therapy Parkinson's disease STN = subthalamic nucleus STN stimulation Subthalamic Nucleus - physiology Treatment Outcome UPDRS = Unified Parkinson's Disease Rating Scale
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