Activation of myocardial constitutive nitric oxide synthase during coronary artery surgery

Objective: The role of nitric oxide (NO) in myocardial ischemia/reperfusion is controversial. While some studies have shown cardioprotective effects of NO, others suggested that increased myocardial NO release secondary to ischemia may contribute to reperfusion injury. However, the impact of cardiop...

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Veröffentlicht in:	European journal of cardio-thoracic surgery 2000-03, Vol.17 (3), p.305-311
Hauptverfasser:	Mehlhorn, Uwe, Bloch, Wilhelm, Krahwinkel, Andreas, LaRose, Karl, Geissler, Hans-Joachim, Hekmat, Khosro, Addicks, Klaus, de Vivie, E. Rainer
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Aged Cardioplegia Cardiopulmonary bypass Coronary Artery Bypass - methods Heart Arrest, Induced Humans Ischemia Middle Aged Myocardial protection Myocardial Reperfusion Injury - prevention & control Myocardium - enzymology Nerve Tissue Proteins - metabolism Nitric oxide synthase Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type I Propanolamines - therapeutic use Reperfusion β-Blocker
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