Phenotypic data in FlyBase

Phenotypic analysis combined with molecular genetics is a powerful tool for mapping gene function onto the genome. Phenotypic data are, by their nature, descriptive, and as varied as the range of mutant phenotypes that can be presented by the organism under study. This paper discusses the mechanisms...

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Veröffentlicht in:Briefings in bioinformatics 2001-03, Vol.2 (1), p.68-80
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description Phenotypic analysis combined with molecular genetics is a powerful tool for mapping gene function onto the genome. Phenotypic data are, by their nature, descriptive, and as varied as the range of mutant phenotypes that can be presented by the organism under study. This paper discusses the mechanisms FlyBase has implemented to systematise published phenotypic data about Drosophila, and provides an introduction to the query tools available for the mining of the data. Though FlyBase is specific to Drosophila, the issues faced in devising protocols for capturing, storing and reporting data are the same issues faced by any database with an interest in using phenotypic data to maximise the potential of genomic analysis.
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source Oxford Journals Open Access Collection; MEDLINE; EZB-FREE-00999 freely available EZB journals; EBSCOhost Business Source Complete
subjects Alleles
Analysis
Animals
Bioinformatics
Computational Biology
Databases, Factual
Drosophila
Drosophila - genetics
Genes, Insect
Genetic Engineering
Genetics
Genome
Genotype
Phenotype
title Phenotypic data in FlyBase
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