Characterization of the Promoter-Directing Expression of Growth Hormone in a Monocyte Cell Line

Previous work from our laboratory has shown that cells of the immune system produce a growth hormone (GH) molecule similar to that produced by the pituitary. In the present study, using Southern analysis of RT-PCR products and sequencing of cloned cDNA molecules, we demonstrate that lymphoid cell li...

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Veröffentlicht in:	Neuroimmunomodulation 2000-01, Vol.7 (3), p.126-134
Hauptverfasser:	Weigent, Douglas A., Vines, Clifford R., Long, Jay C., Blalock, J. Edwin, Elton, Terry S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autocrine Communication Base Sequence Blotting, Southern DNA, Complementary - genetics DNA-Binding Proteins - physiology Electroporation Exons - genetics Gene Expression Regulation Gene Expression Regulation, Neoplastic Genes, Reporter Growth Hormone - biosynthesis Growth Hormone - genetics Luciferases - biosynthesis Luciferases - genetics Macrophages - metabolism Mice Molecular Sequence Data Monocytes - metabolism Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Organ Specificity Original Paper Pituitary Gland, Anterior - metabolism Pituitary Neoplasms - metabolism Pituitary Neoplasms - pathology Promoter Regions, Genetic Rats Recombinant Fusion Proteins - biosynthesis Reverse Transcriptase Polymerase Chain Reaction Transcription Factor Pit-1 Transcription Factors - physiology Transcription, Genetic Tumor Cells, Cultured
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