PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme

Glioblastoma multiforme (GBM), a malignant astrocytic tumour, represents the most frequent tumour of the human brain. Nevertheless, its molecular pathology is not well understood. We utilized the immune system, which contributes to cancer protection, to help identify new GBM-related genes. By screen...

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Veröffentlicht in:	Oncogene 2001-07, Vol.20 (31), p.4107-4114
Hauptverfasser:	STRUSS, A-K, ROMEIKE, B. F. M, MUNNIA, A, NASTAINCZYK, W, STEUDEL, W-I, KÖNIG, J, OHGAKI, H, FEIDEN, W, FISCHER, U, MEESE, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amino acid sequence Antibodies Antibody response Antigens Base Sequence Biological and medical sciences Blood-brain barrier Blotting, Western Brain cancer Brain Neoplasms - blood Brain Neoplasms - genetics Brain Neoplasms - immunology Brain tumors Cloning DNA Primers Female Fundamental and applied biological sciences. Psychology Fundamental immunology Genetics of the immune response Glioblastoma Glioblastoma - blood Glioblastoma - genetics Glioblastoma - immunology glioblastoma multiforme Homology Humans Immune system Immunobiology Immunogenicity Immunohistochemistry Localization Male Middle Aged Paraffin Patients PHF3 gene Polyclonal antibodies Prognosis Proline Proteins Transcription factors Tumors
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