Imaging and Estimation of the Prognostic Features of Primary Sclerosing Cholangitis by Ultrasonography and Mr Cholangiography

AbstractPurpose: To evaluate the ability of US and MR cholangiography (MRC) to detect bile duct changes and prognostic signs of primary sclerosing cholangitis (PSC) seen at endoscopic retrograde cholangiography (ERC).Material and Methods: In a prospective study, 9 patients with PSC underwent US, MRC...

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Veröffentlicht in:Acta radiologica (1987) 2001-07, Vol.42 (4), p.403-408
Hauptverfasser: Oikarinen, H., Pääkkö, E., Suramo, I., Päivänsalo, M., Tervonen, O., Lehtola, J., Aukee, J.
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container_end_page 408
container_issue 4
container_start_page 403
container_title Acta radiologica (1987)
container_volume 42
creator Oikarinen, H.
Pääkkö, E.
Suramo, I.
Päivänsalo, M.
Tervonen, O.
Lehtola, J.
Aukee, J.
description AbstractPurpose: To evaluate the ability of US and MR cholangiography (MRC) to detect bile duct changes and prognostic signs of primary sclerosing cholangitis (PSC) seen at endoscopic retrograde cholangiography (ERC).Material and Methods: In a prospective study, 9 patients with PSC underwent US, MRC, MR imaging and ERC of the bile ducts and the liver. Eight age- and sex-matched control patients were examined with MRC, MR imaging and ERC. A segmental comparison was performed to assess the ability of MRC-MR and US to reveal the accurate ductal involvement in different segments of the biliary tree and the specific criteria of poor prognostic outcome in PSC. The ability of MRC-MR to detect the presence of PSC in different patients was analysed blindly.Results: MRC-MR depicted changes of PSC correctly in 9 patients (radiologist 1) and in 8 patients with 1 false-positive finding (radiologist 2) in the blinded analysis. In the segmental comparison, MRC missed especially bile duct dilatations. MRC was too pessimistic in the evaluation of the outcome. US detected features suggestive of PSC in 8 patients (radiologist 3). US was unable to show the predictors of poor outcome.Conclusion: MRC and US seem to be useful in the detection of PSC. US is unable and MRC is too pessimistic to estimate the outcome of PSC.
doi_str_mv 10.1080/028418501127346891
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Eight age- and sex-matched control patients were examined with MRC, MR imaging and ERC. A segmental comparison was performed to assess the ability of MRC-MR and US to reveal the accurate ductal involvement in different segments of the biliary tree and the specific criteria of poor prognostic outcome in PSC. The ability of MRC-MR to detect the presence of PSC in different patients was analysed blindly.Results: MRC-MR depicted changes of PSC correctly in 9 patients (radiologist 1) and in 8 patients with 1 false-positive finding (radiologist 2) in the blinded analysis. In the segmental comparison, MRC missed especially bile duct dilatations. MRC was too pessimistic in the evaluation of the outcome. US detected features suggestive of PSC in 8 patients (radiologist 3). US was unable to show the predictors of poor outcome.Conclusion: MRC and US seem to be useful in the detection of PSC. US is unable and MRC is too pessimistic to estimate the outcome of PSC.</description><identifier>ISSN: 0284-1851</identifier><identifier>EISSN: 1600-0455</identifier><identifier>DOI: 10.1080/028418501127346891</identifier><identifier>PMID: 11442466</identifier><identifier>CODEN: ACRAE3</identifier><language>eng</language><publisher>London, England: Informa UK Ltd</publisher><subject>Adult ; Bile Ducts - diagnostic imaging ; Bile Ducts - pathology ; Biological and medical sciences ; Cholangiopancreatography, Endoscopic Retrograde ; Cholangitis, Sclerosing - diagnosis ; Cholangitis, Sclerosing - diagnostic imaging ; Digestive system ; False Negative Reactions ; False Positive Reactions ; Female ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Prognosis ; Prospective Studies ; Radiodiagnosis. Nmr imagery. Nmr spectrometry ; Ultrasonography</subject><ispartof>Acta radiologica (1987), 2001-07, Vol.42 (4), p.403-408</ispartof><rights>2001 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2001</rights><rights>Acta Radiologica</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-1ff8945cdf2219d6dcb08be5b5fb9dd78f2f7065fc7bdfaaff7fee8d5ebccd843</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/028418501127346891$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/028418501127346891$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,61194,61375</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=1061083$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11442466$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oikarinen, H.</creatorcontrib><creatorcontrib>Pääkkö, E.</creatorcontrib><creatorcontrib>Suramo, I.</creatorcontrib><creatorcontrib>Päivänsalo, M.</creatorcontrib><creatorcontrib>Tervonen, O.</creatorcontrib><creatorcontrib>Lehtola, J.</creatorcontrib><creatorcontrib>Aukee, J.</creatorcontrib><title>Imaging and Estimation of the Prognostic Features of Primary Sclerosing Cholangitis by Ultrasonography and Mr Cholangiography</title><title>Acta radiologica (1987)</title><addtitle>Acta Radiol</addtitle><description>AbstractPurpose: To evaluate the ability of US and MR cholangiography (MRC) to detect bile duct changes and prognostic signs of primary sclerosing cholangitis (PSC) seen at endoscopic retrograde cholangiography (ERC).Material and Methods: In a prospective study, 9 patients with PSC underwent US, MRC, MR imaging and ERC of the bile ducts and the liver. Eight age- and sex-matched control patients were examined with MRC, MR imaging and ERC. A segmental comparison was performed to assess the ability of MRC-MR and US to reveal the accurate ductal involvement in different segments of the biliary tree and the specific criteria of poor prognostic outcome in PSC. The ability of MRC-MR to detect the presence of PSC in different patients was analysed blindly.Results: MRC-MR depicted changes of PSC correctly in 9 patients (radiologist 1) and in 8 patients with 1 false-positive finding (radiologist 2) in the blinded analysis. In the segmental comparison, MRC missed especially bile duct dilatations. MRC was too pessimistic in the evaluation of the outcome. US detected features suggestive of PSC in 8 patients (radiologist 3). US was unable to show the predictors of poor outcome.Conclusion: MRC and US seem to be useful in the detection of PSC. US is unable and MRC is too pessimistic to estimate the outcome of PSC.</description><subject>Adult</subject><subject>Bile Ducts - diagnostic imaging</subject><subject>Bile Ducts - pathology</subject><subject>Biological and medical sciences</subject><subject>Cholangiopancreatography, Endoscopic Retrograde</subject><subject>Cholangitis, Sclerosing - diagnosis</subject><subject>Cholangitis, Sclerosing - diagnostic imaging</subject><subject>Digestive system</subject><subject>False Negative Reactions</subject><subject>False Positive Reactions</subject><subject>Female</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Radiodiagnosis. Nmr imagery. Nmr spectrometry</subject><subject>Ultrasonography</subject><issn>0284-1851</issn><issn>1600-0455</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUtv1DAUhS1ERYfCH2CBvEDsQn09duJIbNCohUpFrVS6jhw_klSJPdjOYhb973hIBEhI0JWl6--c-zgIvQHyAYgg54QKBoITAFptWSlqeIY2UBJSEMb5c7Q5AkUm4BS9jPGBkAxyeIFOARijrCw36PFqkt3gOiydxhcxDZNMg3fYW5x6g2-D75zPZYUvjUxzMPH4dRsyFw74To0m-HjU73o_StcNaYi4PeD7MQUZvfNdkPv-8NP-a_hFreVX6MTKMZrX63uG7i8vvu2-FNc3n692n64LxThNBVgrasaVtpRCrUutWiJaw1tu21rrSlhqK1Jyq6pWWymtrawxQnPTKqUF256h94vvPvjvs4mpmYaozJhnMX6OTQUEqi38H4S6hApqmkG6gCrvH4OxzX65SQOkOabT_J1OFr1d3ed2Mvq3ZI0jA-9WQEYlRxukU0P8w7rM1tuMnS9YlJ1pHvwcXL7evzt_XBSDsz5MsjdyTL2S4WnyHwKRuqQ</recordid><startdate>20010701</startdate><enddate>20010701</enddate><creator>Oikarinen, H.</creator><creator>Pääkkö, E.</creator><creator>Suramo, I.</creator><creator>Päivänsalo, M.</creator><creator>Tervonen, O.</creator><creator>Lehtola, J.</creator><creator>Aukee, J.</creator><general>Informa UK Ltd</general><general>SAGE Publications</general><general>Taylor &amp; Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20010701</creationdate><title>Imaging and Estimation of the Prognostic Features of Primary Sclerosing Cholangitis by Ultrasonography and Mr Cholangiography</title><author>Oikarinen, H. ; Pääkkö, E. ; Suramo, I. ; Päivänsalo, M. ; Tervonen, O. ; Lehtola, J. ; Aukee, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-1ff8945cdf2219d6dcb08be5b5fb9dd78f2f7065fc7bdfaaff7fee8d5ebccd843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Bile Ducts - diagnostic imaging</topic><topic>Bile Ducts - pathology</topic><topic>Biological and medical sciences</topic><topic>Cholangiopancreatography, Endoscopic Retrograde</topic><topic>Cholangitis, Sclerosing - diagnosis</topic><topic>Cholangitis, Sclerosing - diagnostic imaging</topic><topic>Digestive system</topic><topic>False Negative Reactions</topic><topic>False Positive Reactions</topic><topic>Female</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Radiodiagnosis. Nmr imagery. Nmr spectrometry</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oikarinen, H.</creatorcontrib><creatorcontrib>Pääkkö, E.</creatorcontrib><creatorcontrib>Suramo, I.</creatorcontrib><creatorcontrib>Päivänsalo, M.</creatorcontrib><creatorcontrib>Tervonen, O.</creatorcontrib><creatorcontrib>Lehtola, J.</creatorcontrib><creatorcontrib>Aukee, J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Acta radiologica (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oikarinen, H.</au><au>Pääkkö, E.</au><au>Suramo, I.</au><au>Päivänsalo, M.</au><au>Tervonen, O.</au><au>Lehtola, J.</au><au>Aukee, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Imaging and Estimation of the Prognostic Features of Primary Sclerosing Cholangitis by Ultrasonography and Mr Cholangiography</atitle><jtitle>Acta radiologica (1987)</jtitle><addtitle>Acta Radiol</addtitle><date>2001-07-01</date><risdate>2001</risdate><volume>42</volume><issue>4</issue><spage>403</spage><epage>408</epage><pages>403-408</pages><issn>0284-1851</issn><eissn>1600-0455</eissn><coden>ACRAE3</coden><abstract>AbstractPurpose: To evaluate the ability of US and MR cholangiography (MRC) to detect bile duct changes and prognostic signs of primary sclerosing cholangitis (PSC) seen at endoscopic retrograde cholangiography (ERC).Material and Methods: In a prospective study, 9 patients with PSC underwent US, MRC, MR imaging and ERC of the bile ducts and the liver. Eight age- and sex-matched control patients were examined with MRC, MR imaging and ERC. A segmental comparison was performed to assess the ability of MRC-MR and US to reveal the accurate ductal involvement in different segments of the biliary tree and the specific criteria of poor prognostic outcome in PSC. The ability of MRC-MR to detect the presence of PSC in different patients was analysed blindly.Results: MRC-MR depicted changes of PSC correctly in 9 patients (radiologist 1) and in 8 patients with 1 false-positive finding (radiologist 2) in the blinded analysis. In the segmental comparison, MRC missed especially bile duct dilatations. MRC was too pessimistic in the evaluation of the outcome. US detected features suggestive of PSC in 8 patients (radiologist 3). US was unable to show the predictors of poor outcome.Conclusion: MRC and US seem to be useful in the detection of PSC. US is unable and MRC is too pessimistic to estimate the outcome of PSC.</abstract><cop>London, England</cop><pub>Informa UK Ltd</pub><pmid>11442466</pmid><doi>10.1080/028418501127346891</doi><tpages>6</tpages></addata></record>
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source Taylor & Francis:Master (3349 titles); MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Adult
Bile Ducts - diagnostic imaging
Bile Ducts - pathology
Biological and medical sciences
Cholangiopancreatography, Endoscopic Retrograde
Cholangitis, Sclerosing - diagnosis
Cholangitis, Sclerosing - diagnostic imaging
Digestive system
False Negative Reactions
False Positive Reactions
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Middle Aged
Prognosis
Prospective Studies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Ultrasonography
title Imaging and Estimation of the Prognostic Features of Primary Sclerosing Cholangitis by Ultrasonography and Mr Cholangiography
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