Mesenteric dysfunction after cardiopulmonary bypass: role of complement C5a

Background. We investigated the effects of cardiopulmonary bypass (CPB) on ileal homeostasis, and the influence of functional inhibition of complement C5a on CPB-induced mesenteric injury. Methods. Pigs were perfused on CPB for 1 hour and then perfused off CPB for an additional 2 hours. Antiporcine...

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Veröffentlicht in:	The Annals of thoracic surgery 2000-03, Vol.69 (3), p.799-807
Hauptverfasser:	Tofukuji, Motohisa, Stahl, Gregory L, Metais, Caroline, Tomita, Mikio, Agah, Azin, Bianchi, Cesario, Fink, Mitchell P, Sellke, Frank W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia depending on type of surgery Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Capillary Permeability Cardiopulmonary Bypass - adverse effects Complement C5a - physiology Female Ileum - blood supply Intestinal Mucosa - physiopathology Male Medical sciences Mesenteric Arteries - physiopathology Postoperative Complications - etiology Postoperative Complications - physiopathology Splanchnic Circulation Swine Thoracic and cardiovascular surgery. Cardiopulmonary bypass
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