Activity of gatifloxacin against strains resistant to ofloxacin and ciprofloxacin and its ability to select for less susceptible bacterial variants

Gatifloxacin is an 8-methoxy fluoroquinolone. On quinolones, this side chain imparts increased activity against Gram-positive bacteria and enhanced killing. Gatifloxacin was tested against ofloxacin non-susceptible (ofloxacin MIC>2 mg/l) strains of Streptococcus pneumoniae (gatifloxacin MIC 90, 1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of antimicrobial agents 2001-07, Vol.18 (1), p.77-80
Hauptverfasser:	Fung-Tomc, J, Gradelski, E, Huczko, E, Minassian, B, Bonner, D.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Ciprofloxacin - pharmacology Drug Resistance, Microbial Escherichia coli - drug effects Escherichia coli - genetics Fluoroquinolones Gatifloxacin Medical sciences Methicillin Resistance Microbial Sensitivity Tests Mutation Neisseria gonorrhoeae - drug effects Neisseria gonorrhoeae - genetics Ofloxacin - pharmacology Pharmacology. Drug treatments Quinolones Resistance Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Streptococcus pneumoniae Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!