Effect of prolonged hypoxia on Na + channel mRNA subtypes in the developing rat cortex

Voltage-gated Na + channels are regulated in response to oxygen deprivation in the mammalian cortex. Past investigations have demonstrated that Na + channel protein expression is up-regulated in the immature brain exposed to prolonged hypoxia. Since it is unknown as to which Na + channel subtype(s)...

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Veröffentlicht in:	Brain research. Molecular brain research. 2001-07, Vol.91 (1), p.154-158
Hauptverfasser:	Zhang, J.H, Gibney, G.T, Xia, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Cerebral Cortex - growth & development Cerebral Cortex - physiopathology Cortex Development Development. Senescence. Regeneration. Transplantation DNA Primers Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Hypoxia Hypoxia, Brain - physiopathology mRNA expression Rats Rats, Sprague-Dawley RNA, Messenger - analysis Sodium channel Sodium Channels - genetics Vertebrates: nervous system and sense organs
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