Solution Structure and Backbone Dynamics of Long-[Arg3]insulin-like Growth Factor-I

Long-[Arg3]insulin-like growth factor-I (IGF-I) is a potent analog of insulin-like growth factor-I that has been modified by a Glu3 → Arg mutation and a 13-amino acid extension appended to the N terminus. We have determined the solution structure of 15N-labeled Long-[Arg3]-IGF-I using high resolutio...

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Veröffentlicht in:	The Journal of biological chemistry 2000-04, Vol.275 (14), p.10009-10015
Hauptverfasser:	Laajoki, Leanne G., Francis, Geoffrey L., Wallace, John C., Carver, John A., Keniry, Max A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Insulin-Like Growth Factor I - analogs & derivatives Insulin-Like Growth Factor I - chemistry Models, Molecular Molecular Sequence Data Nuclear Magnetic Resonance, Biomolecular Protein Structure, Secondary Solutions
Online-Zugang:	Volltext
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