Effect of Aerosolized Uridine 5'-Triphosphate on Mucociliary Clearance in Mild Chronic Bronchitis

Previous studies show that uridine 5'-triphosphate (UTP), a P2Y(2) receptor agonist, is effective at acutely enhancing mucociliary clearance in healthy, nonsmoking adults. UTP solution for inhalation is being developed by Inspire Pharmaceuticals under the compound number INS316. In a double-bli...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2001-07, Vol.164 (2), p.302-306
Hauptverfasser:	BENNETT, WILLIAM D, ZEMAN, KIRBY L, FOY, CARLA, SHAFFER, CHRISTY L, JOHNSON, FRED L, REGNIS, JEFF A, SANNUTI, ARUNA, JOHNSON, JANA
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Adult Biological and medical sciences Bronchitis - drug therapy Bronchitis - physiopathology Chronic Disease Cross-Over Studies Double-Blind Method Female Humans Male Medical sciences Middle Aged Mucociliary Clearance - drug effects Pharmacology. Drug treatments Respiratory system Severity of Illness Index Uridine Triphosphate - administration & dosage
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