Analysis of skin permeation-enhancing mechanism of iontophoresis using hydrodynamic pore theory

The effects of constant DC iontophoresis (0–1.5 mA/0.966 cm 2) on the permeation of three hydrophilic compounds, antipyrine (ANP, M.W. 188.23), sucrose (SR, M.W. 342.30) and 1-kestose (KT, M.W. 506.73), through excised hairless rat skin were evaluated using hydrodynamic pore theory. The electro-osmo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of controlled release 2000-05, Vol.66 (2), p.149-158
Hauptverfasser:	Manabe, Eiichiro, Numajiri, Sachihiko, Sugibayashi, Kenji, Morimoto, Yasunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Biological and medical sciences Drug Delivery Systems Electro-osmotic flow General pharmacology Hydrodynamic pore theory Iontophoresis Male Medical sciences Models, Biological Permeability Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rats Skin - metabolism Skin permeation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!