N- and C-terminal Domains Direct Cell Type-specific Sorting of Chromogranin A to Secretory Granules

Chromogranins are a family of regulated secretory proteins that are stored in secretory granules in endocrine and neuroendocrine cells and released in response to extracellular stimulation (regulated secretion). A conserved N-terminal disulfide bond is necessary for sorting of chromogranins in neuro...

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