Differential Assembly of Human Tau Isoforms in the Presence of Arachidonic Acid

: Six tau isoforms arise from the alternative splicing of a single gene in humans. Insoluble, filamentous deposits of tau protein occur in a number of neuro‐degenerative diseases, and in some of these diseases, the deposition of polymers enriched in certain tau isoforms has been documented. Because...

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Veröffentlicht in:	Journal of neurochemistry 2000-04, Vol.74 (4), p.1749-1757
Hauptverfasser:	King, Michelle E., Gamblin, T. Chris, Kuret, Jeff, Binder, Lester I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - drug effects Actin Cytoskeleton - metabolism Actin Cytoskeleton - ultrastructure Adult Arachidonic acid Arachidonic Acid - pharmacology Biological and medical sciences Cell Line Cell structures and functions Cytoskeleton, cytoplasm. Intracellular movements Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Isomerism Microscopy, Electron Molecular and cellular biology Neurofibrillary Tangles - drug effects Neurofibrillary Tangles - metabolism Neurofibrillary Tangles - ultrastructure Tau Tau isoforms tau Proteins - chemistry tau Proteins - metabolism tau Proteins - ultrastructure
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