Studies on the Total Synthesis of Formamicin:  Synthesis of the C(1)−C(11) Fragment

An efficient and highly concise synthesis of 6, corresponding to the C(1)−C(11) fragment of formamicin (1), has been accomplished by a route utilizing a diastereoselective lactate aldol reaction to set the C(6) tertiary ether and the TES−OTf mediated transketalization of the C(6) tertiary methoxymet...

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Veröffentlicht in:	Organic letters 2001-02, Vol.3 (3), p.453-456
Hauptverfasser:	Powell, Noel A, Roush, William R
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - chemistry Anti-Bacterial Agents - chemical synthesis Antifungal Agents - chemical synthesis Macrolides
Online-Zugang:	Volltext
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