Structural Relationships and Sialylation among Meningococcal L1, L8, and L3,7 Lipooligosaccharide Serotypes

Eighteen of 34 endemic meningococcal case strains were of the L8 lipooligosaccharide (LOS) type; four of these were both L3 and L7 (L3,7), and seven were L1. L1 structures arose by alternative terminal Gal substitutions of lactosyl diheptoside L8 structures, as determined by electrospray ionization...

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Veröffentlicht in:	The Journal of biological chemistry 2000-03, Vol.275 (13), p.9716-9724
Hauptverfasser:	Griffiss, J.McLeod, Brandt, Brenda L., Saunders, Nancy B., Zollinger, Wendell
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrate Conformation Carbohydrate Sequence Electrophoresis, Polyacrylamide Gel endemics Glycoside Hydrolases - chemistry Hydrolysis lactosyl diheptoside L8 lipooligosaccharides Lipopolysaccharides - chemistry Mass Spectrometry Molecular Sequence Data N-Acetylneuraminic Acid - chemistry Neisseria meningitidis Neisseria meningitidis - chemistry sialylation
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