Use of microalbuminuria as a predictor of outcome in critically ill patients
We have investigated the use of microalbuminuria as a predictor of outcome in a pilot study involving 50 critically ill patients in a six-bed hospital intensive care unit (ICU). Urinary microalbumin:creatinine (M:Cr) ratios measured only 6 h after admission to the ICU demonstrated a significant diff...
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| Veröffentlicht in: | British Journal of Anaesthesia 2000-02, Vol.84 (2), p.239-241 |
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| container_title | British Journal of Anaesthesia |
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| creator | MacKinnon, K L Molnar, Z Lowe, D Watson, I D Shearer, E |
| description | We have investigated the use of microalbuminuria as a predictor of outcome in a pilot study involving 50 critically ill patients in a six-bed hospital intensive care unit (ICU). Urinary microalbumin:creatinine (M:Cr) ratios measured only 6 h after admission to the ICU demonstrated a significant difference (P = 0.01) between survivors and non-survivors, allowing rapid identification of patients at increased risk of developing organ failure and at greater risk of death. This work suggests that earlier identification of these patients using a rapid, simple, inexpensive biochemical test is possible; if confirmed in a larger study, it may be that clinical interventions can be targeted at those most likely to benefit. |
| doi_str_mv | 10.1093/oxfordjournals.bja.a013409 |
| format | Article |
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Urinary microalbumin:creatinine (M:Cr) ratios measured only 6 h after admission to the ICU demonstrated a significant difference (P = 0.01) between survivors and non-survivors, allowing rapid identification of patients at increased risk of developing organ failure and at greater risk of death. This work suggests that earlier identification of these patients using a rapid, simple, inexpensive biochemical test is possible; if confirmed in a larger study, it may be that clinical interventions can be targeted at those most likely to benefit.</description><identifier>ISSN: 0007-0912</identifier><identifier>EISSN: 1471-6771</identifier><identifier>DOI: 10.1093/oxfordjournals.bja.a013409</identifier><identifier>PMID: 10743459</identifier><identifier>CODEN: BJANAD</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Adult ; Aged ; Albuminuria - diagnosis ; Albuminuria - mortality ; Biological and medical sciences ; Biomarkers - urine ; Critical Care - methods ; Critical Illness - mortality ; Hospital Mortality ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Logistic Models ; Medical sciences ; Middle Aged ; Pathology. Cytology. Biochemistry. Spectrometry. 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Urinary microalbumin:creatinine (M:Cr) ratios measured only 6 h after admission to the ICU demonstrated a significant difference (P = 0.01) between survivors and non-survivors, allowing rapid identification of patients at increased risk of developing organ failure and at greater risk of death. This work suggests that earlier identification of these patients using a rapid, simple, inexpensive biochemical test is possible; if confirmed in a larger study, it may be that clinical interventions can be targeted at those most likely to benefit.</description><subject>Adult</subject><subject>Aged</subject><subject>Albuminuria - diagnosis</subject><subject>Albuminuria - mortality</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - urine</subject><subject>Critical Care - methods</subject><subject>Critical Illness - mortality</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Logistic Models</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. 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| issn | 0007-0912 1471-6771 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adult Aged Albuminuria - diagnosis Albuminuria - mortality Biological and medical sciences Biomarkers - urine Critical Care - methods Critical Illness - mortality Hospital Mortality Humans Investigative techniques, diagnostic techniques (general aspects) Logistic Models Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pilot Projects Prognosis Urinary system |
| title | Use of microalbuminuria as a predictor of outcome in critically ill patients |
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