Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy

Role of glomerular ultrafiltration of growth factors in progressive interstitial fibrosis in diabetic nephropathy. The present in vivo and in vitro experiments were performed to test the hypothesis that in rats with glomerular proteinuria, the bioactive growth factors transforming growth factor-β (T...

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Veröffentlicht in:	Kidney international 2000-03, Vol.57 (3), p.1002-1014
Hauptverfasser:	Wang, Shi-Nong, Lapage, Janine, Hirschberg, Raimund
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Associated diseases and complications Biological and medical sciences Body Fluids - metabolism Chemokine CCL2 - metabolism Chemokine CCL5 - metabolism Diabetes. Impaired glucose tolerance Diabetic Nephropathies - metabolism Diabetic Nephropathies - pathology diabetic nephropathy Disease Progression Endocrine pancreas. Apud cells (diseases) Endocrinopathies Extracellular Matrix Proteins - metabolism fibronectin Fibrosis - metabolism Glomerulonephritis hepatocyte growth factor Hepatocyte Growth Factor - metabolism Humans Kidney - cytology Kidney - metabolism Kidney Glomerulus - metabolism Kidney Tubules, Proximal - metabolism MCP-1 Medical sciences Mice Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure proteinuria Proto-Oncogene Proteins c-met - metabolism Rats Rats, Sprague-Dawley Receptors, Transforming Growth Factor beta - metabolism TGF-β Transforming Growth Factor beta - metabolism
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