Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer’s dementia

We investigated the immunohistochemical alterations of angiotensin converting enzyme (ACE), angiotensin II and AT1 receptor in the parietal cortex in Alzheimer’s dementia (AD) to reveal the contributive role of the brain renin-angiotensin system in the disease process. In controls, ACE, angiotensin...

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Veröffentlicht in:	Neurobiology of aging 2001-07, Vol.22 (4), p.541-546
Hauptverfasser:	Savaskan, Egemen, Hock, Christoph, Olivieri, Gianfranco, Bruttel, Sybille, Rosenberg, Carolyn, Hulette, Christine, Müller-Spahn, Franz
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - metabolism Alzheimer Disease - pathology Alzheimer’s dementia Angiotensin II - analysis Angiotensin II - metabolism angiotensin-converting enzyme Biological and medical sciences Cerebral Cortex - chemistry Cerebral Cortex - metabolism Cerebral Cortex - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Humans Immunohistochemistry Male Medical sciences Middle Aged Neurology Peptidyl-Dipeptidase A - analysis Peptidyl-Dipeptidase A - metabolism Receptor, Angiotensin, Type 1 Receptor, Angiotensin, Type 2 Receptors, Angiotensin - analysis Receptors, Angiotensin - metabolism Renin-Angiotensin System
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