Hippocampal formation glucose metabolism and volume losses in MCI and AD

We used MRI volume sampling with coregistered and atrophy corrected FDG-PET scans to test three hypotheses: 1) hippocampal formation measures are superior to temporal neocortical measures in the discrimination of normal (NL) and mild cognitive impairment (MCI); 2) neocortical measures are most usefu...

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Veröffentlicht in:	Neurobiology of aging 2001-07, Vol.22 (4), p.529-539
Hauptverfasser:	De Santi, Susan, de Leon, Mony J, Rusinek, Henry, Convit, Antonio, Tarshish, Chaim Y, Roche, Alexandra, Tsui, Wai Hon, Kandil, Emad, Boppana, Madhu, Daisley, Katherine, Wang, Gene Jack, Schlyer, David, Fowler, Joanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - diagnostic imaging Alzheimer Disease - metabolism Alzheimer Disease - pathology Atrophy Biological and medical sciences Cognition Disorders - diagnostic imaging Cognition Disorders - metabolism Cognition Disorders - pathology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Early diagnosis of Alzheimer’s disease Female Glucose - metabolism Hippocampal formation Hippocampus - metabolism Hippocampus - pathology Humans Magnetic Resonance Imaging Male Medical sciences Middle Aged Mild cognitive impairment MRI Neurology PET Predictive Value of Tests Sensitivity and Specificity Tomography, Emission-Computed
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