Effect of Testicular Macrophage Conditioned Media from Rats with Autoimmune Orchitis on Leydig Cell Function

PROBLEM: The aim of this study was to investigate the influence of immune‐activated testicular macrophages obtained from rats with autoimmune orchitis (EAO) on Leydig cell steroidogenesis. METHOD OF STUDY: EAO was induced in rats by active immunization with testis homogenate and adjuvants. Testicula...

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Veröffentlicht in:	American journal of reproductive immunology (1989) 2000-02, Vol.43 (2), p.116-123
Hauptverfasser:	SUESCUN, MARÍA O., CALANDRA, RICARDO S., LUSTIG, LIVIA
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmune Diseases - immunology autoimmune orchitis Biological and medical sciences Cells, Cultured Chorionic Gonadotropin - pharmacology Culture Media, Conditioned - chemistry Culture Media, Conditioned - pharmacology Dose-Response Relationship, Immunologic Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Leydig cells Leydig Cells - drug effects Leydig Cells - immunology Leydig Cells - metabolism macrophage-Leydig cell interaction macrophages Macrophages - immunology Macrophages - secretion Macrophages, Peritoneal - immunology Macrophages, Peritoneal - secretion Male Mammalian male genital system Orchitis - immunology Rats Rats, Sprague-Dawley steroidogenesis testis Testis - immunology Testosterone - antagonists & inhibitors Testosterone - biosynthesis Vertebrates: reproduction
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