Crystallization and preliminary X-ray analysis of the catalytic domain of the adenylate cyclase GRESAG4.1 from Trypanosoma brucei

Adenylate cyclases (ACs) are involved in signal transduction by generating the second messenger, cAMP. In Trypanosoma brucei, 3′,5′‐cyclic adenosine monophosphate (cAMP) controls the life cycle of this unicellular parasite. cAMP is generated by a class of adenylate cyclases which are either constitu...

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Veröffentlicht in:	Acta crystallographica. Section D, Biological crystallography. Biological crystallography., 2000-03, Vol.56 (3), p.359-362
Hauptverfasser:	Bieger, Boris, Essen, Lars-Oliver
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - chemistry Adenylyl Cyclases - isolation & purification Amino Acid Sequence Animals Catalysis Crystallization Crystallography, X-Ray Escherichia coli Mass Spectrometry Models, Molecular Molecular Sequence Data Peptide Fragments - chemistry Peptide Fragments - isolation & purification Protein Conformation Protein Folding Protein Structure, Tertiary Protozoan Proteins - chemistry Protozoan Proteins - isolation & purification Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - isolation & purification Sequence Alignment Sequence Homology, Amino Acid Species Specificity Trypanosoma brucei brucei - enzymology
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