Hemodynamic, hormonal, and renal effects of short-term adrenomedullin infusion in healthy volunteers

The actions of adrenomedullin (ADM), a 52-amino acid peptide, are not well defined in man. We, therefore, studied eight normal volunteers aged 1832 yr in a placebo-controlled crossover study. On the 2 study days, subjects received, in random order, ADM in "low" and "high" dose (2...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2000-03, Vol.85 (3), p.1016-1020
Hauptverfasser:	LAINCHBURY, J. G, TROUGHTON, R. W, LEWIS, L. K, YANDLE, T. G, RICHARDS, A. M, NICHOLLS, M. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenomedullin Adult Biological and medical sciences Blood Pressure - drug effects Cross-Over Studies Endocrinopathies General aspects. Associated endocrine diseases. Endocrine paraneoplasic syndromes Heart Rate - drug effects Hemodynamics - drug effects Hormones - blood Humans Injections, Intravenous Kidney - drug effects Kidney - metabolism Male Medical sciences Peptides - administration & dosage Peptides - blood Peptides - pharmacology Recombinant Proteins - pharmacology Tropical medicine Urodynamics - drug effects Vasodilator Agents - administration & dosage Vasodilator Agents - blood Vasodilator Agents - pharmacology
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