Isolation and identification of poly-α-(1→4)-linked 3- O-methyl- d-mannopyranose from a hot-water extract of Mycobacterium vaccae

A polysaccharide around 3.6 kDa has been identified as the major carbohydrate moiety of a antineoplastic protein–polysaccharide complex (PS4A) obtained by boiling intact cells of Mycobacterium vaccae in water. 1H and 13C NMR spectra of this polysaccharide suggested it was a highly homogeneous polyme...

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Veröffentlicht in:	Carbohydrate research 2000-01, Vol.324 (1), p.38-44
Hauptverfasser:	Tian, Xin-Xin, Li, Afeng, Farrugia, Isabelle V, Mo, Xuesheng, Crich, David, Groves, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - chemistry Carbohydrate Conformation Chromatography, High Pressure Liquid Magnetic Resonance Spectroscopy Mannans - chemistry Methylation Mycobacterium - chemistry Mycobacterium vaccae Poly-α-(1→4)-3- O-methyl mannopyranose Polysaccharides, Bacterial - chemistry Protein–polysaccharide complex Synthesis
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