The role of semen in induction of maternal immune tolerance to pregnancy

Successful pregnancy requires a state of maternal immune ‘tolerance’ to accommodate antigens expressed by the conceptus. Implantation failure and placental pathologies largely reflect insufficiencies in maternal immune adaptation, but progress in devising therapeutic strategies to treat these condit...

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Veröffentlicht in:	Seminars in immunology 2001-08, Vol.13 (4), p.243-254
Hauptverfasser:	Robertson, Sarah A., Sharkey, David J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Cytokines - metabolism embryo / pregnancy / seminal plasma / sperm / tolerance Embryo Implantation - immunology Female Humans Immune Tolerance Lymphocyte Subsets - immunology Male Models, Biological Pregnancy - immunology Pregnancy Outcome Semen - immunology Trophoblasts - immunology
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