Expression of cytokines and factors modulating apoptosis by human sinusoidal leucocytes

Liver sinusoids contain a large population of spontaneously cytotoxic cells (NK cells), CD8+ T cells and macrophages. The physiological role of these leucocytes remains unclear. They may participate in immune surveillance and peripheral tolerance by deleting tumour cells, virus-infected cells and ac...

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Veröffentlicht in:	Journal of hepatology 2000-03, Vol.32 (3), p.392-398
Hauptverfasser:	JONSSON, J. R, EDWARDS-SMITH, C. J, CATANIA, S. C, MOROTOMI, Y, HOGAN, P. G, CLOUSTON, A. D, BANSAL, A. S, LYNCH, S. V, STRONG, R. W, POWELL, E. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - metabolism Apoptosis - physiology Biological and medical sciences Cytokines - genetics Cytokines - metabolism Digestive system Fas Ligand Protein Granzymes Humans Investigative techniques, diagnostic techniques (general aspects) Leukocytes - metabolism Liver - cytology Liver - metabolism Medical sciences Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Perforin Pore Forming Cytotoxic Proteins RNA, Messenger - metabolism Serine Endopeptidases - genetics Serine Endopeptidases - metabolism Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism
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